@era222 If you feel that this is a great opportunity, I'd personally suggest going for it. Don't hold back on possible doors opening up for you. I don't think merong repercussion yan. 🙂
I believe you just need to inform on the change of country of residence (I'm unable confirm the exact link sa ImmiAccount since it's currently under maintenance, but it's one of the options somewhere inside the visa application itself).
Once ma-grant na, dun ka na lang mag plan when you will be permanently moving to Aus, mag first entry ka na lang muna to activate the visa.
Tingin ko hindi ka naman na hihingan ng add'l police check rin for the new country, probably unless mag tagal ka dun for more than a year tapos wala ka pang grant (wag naman sana di ba haha jusko).